Список проголосовавших за комментарий "<p>TERT activation targets DNA methylation and multiple aging hallmarks </p><p>Authors</p><p>Hong Seok Shim, Jonathan Iaconelli, Xiaoying Shang, ..., Michael J. Bollong, Peter G. Schultz, Ronald A. DePinho</p><p>Correspondence rdepinho@mdanderson.org</p><p>In brief</p><p>This study identiﬁes a small molecule (TAC) that restores physiological levels of TERT throughout aged tissues, resulting in the rejuvenation of multiple tissues. Speciﬁcally, TAC administration in very aged mice alleviates multiple aging hallmarks such as cellular senescence and systemic inﬂammation, promotes new neuron formation with improved cognitive ability, enhances neuromuscular function, and is well tolerated with no evidence of toxicity.</p>"